Current status of curcumin in the prevention and treatment of colorectal cancer
①Curcumin can effectively inhibit the development of colorectal cancer (CRC), and its therapeutic effect on CRC has been verified in preclinical and clinical studies;< br />②Curcumin can regulate the intestinal microbial environment, protect the intestinal barrier function, promote the anti-inflammatory activity of the gastrointestinal tract, regulate cancer cell autophagy, target cancer stem cells, act as a chemosensitizer, and regulate cancer cell epigenetics And cell cycle, etc.;
③In multiple clinical trials, curcumin is used to prevent CRC and chemotherapy as a potential natural booster for the development of cancer immunotherapy;
④Curcumin The limitation in cancer prevention and treatment lies in its low absorption and fast metabolism, resulting in low bioavailability.
Document source: https://www.mr-gut.cn/papers/read /1037251817?kf=read_other
